EDITORIALS

Gary C. Sieck

Physiology of aging
J Appl Physiol 95: 1333-1334, 2003; 10.1152/japplphysiol.00718.2003 [Full Text]  

INVITED EDITORIAL

Molly Bogue

Mouse Phenome Project: understanding human biology through mouse genetics and genomics
J Appl Physiol 95: 1335-1337, 2003; 10.1152/japplphysiol.00562.2003 [Full Text]  

MOUSE PHENOME PROJECT

John C. Crabbe, Pamela Metten, Chia-Hua Yu, Jason P. Schlumbohm, Andy J. Cameron, and Douglas Wahlsten

Genotypic differences in ethanol sensitivity in two tests of motor incoordination
J Appl Physiol 95: 1338-1351, 2003. First published April 18, 2003; 10.1152/japplphysiol.00132.2003 [Abstract] [Full Text]  

James W. Watters, Ellen F. Kloss, Daniel C. Link, Timothy A. Graubert, and Howard L. McLeod

A mouse-based strategy for cyclophosphamide pharmacogenomic discovery
J Appl Physiol 95: 1352-1360, 2003; 10.1152/japplphysiol.00214.2003 [Abstract] [Full Text]  

ARTICLES

Minoru Shinohara, Mark L. Latash, and Vladimir M. Zatsiorsky

Age effects on force produced by intrinsic and extrinsic hand muscles and finger interaction during MVC tasks
J Appl Physiol 95: 1361-1369, 2003. First published March 7, 2003; 10.1152/japplphysiol.00070.2003 [Abstract] [Full Text]  

Connie C. W. Hsia, Robert L. Johnson, Jr, Eugene Y. Wu, Aaron S. Estrera, Harrieth Wagner, and Peter D. Wagner

Reducing lung strain after pneumonectomy impairs oxygen diffusing capacity but not ventilation-perfusion matching
J Appl Physiol 95: 1370-1378, 2003. First published June 6, 2003; 10.1152/japplphysiol.00338.2003 [Abstract] [Full Text]  

Sinead C. Barry and Charles G. Gallagher

Corticosteroids and skeletal muscle function in cystic fibrosis
J Appl Physiol 95: 1379-1384, 2003. First published June 13, 2003; 10.1152/japplphysiol.00506.2002 [Abstract] [Full Text]  

Michael R. Wilson, Sharmila Choudhury, Michael E. Goddard, Kieran P. O'Dea, Andrew G. Nicholson, and Masao Takata

High tidal volume upregulates intrapulmonary cytokines in an in vivo mouse model of ventilator-induced lung injury
J Appl Physiol 95: 1385-1393, 2003. First published June 13, 2003; 10.1152/japplphysiol.00213.2003 [Abstract] [Full Text]  

Anna Blasi, Javier Jo, Edwin Valladares, Barbara J. Morgan, James B. Skatrud, and Michael C. K. Khoo

Cardiovascular variability after arousal from sleep: time-varying spectral analysis
J Appl Physiol 95: 1394-1404, 2003. First published June 20, 2003; 10.1152/japplphysiol.01095.2002 [Abstract] [Full Text]  

J. E. Hurst and R. H. Fitts

Hindlimb unloading-induced muscle atrophy and loss of function: protective effect of isometric exercise
J Appl Physiol 95: 1405-1417, 2003. First published June 20, 2003; 10.1152/japplphysiol.00516.2002 [Abstract] [Full Text]  

Petra M. Schmitt and M. P. Kaufman

Estrogen attenuates the exercise pressor reflex in female cats
J Appl Physiol 95: 1418-1424, 2003. First published June 20, 2003; 10.1152/japplphysiol.00368.2003 [Abstract] [Full Text]  

Stephen M. Roth, E. Jeffrey Metter, Mechele R. Lee, Ben F. Hurley, and Robert E. Ferrell

C174T polymorphism in the CNTF receptor gene is associated with fat-free mass in men and women
J Appl Physiol 95: 1425-1430, 2003. First published June 13, 2003; 10.1152/japplphysiol.00516.2003 [Abstract] [Full Text]  

Paula S. McKinley, Peter A. Shapiro, Emilia Bagiella, Michael M. Myers, Ronald E. De Meersman, Igor Grant, and Richard P. Sloan

Deriving heart period variability from blood pressure waveforms
J Appl Physiol 95: 1431-1438, 2003. First published June 27, 2003; 10.1152/japplphysiol.01110.2002 [Abstract] [Full Text]  

William H. Cooke, Guy L. Pellegrini, and Olga A. Kovalenko

Dynamic cerebral autoregulation is preserved during acute head-down tilt
J Appl Physiol 95: 1439-1445, 2003. First published June 27, 2003; 10.1152/japplphysiol.00524.2003 [Abstract] [Full Text]  

Paola Palestini, Chiara Calvi, Elena Conforti, Rossella Daffara, Laura Botto, and Giuseppe Miserocchi

Compositional changes in lipid microdomains of air-blood barrier plasma membranes in pulmonary interstitial edema
J Appl Physiol 95: 1446-1452, 2003. First published June 6, 2003; 10.1152/japplphysiol.00208.2003 [Abstract] [Full Text]  

T Shintani, A. R. Anker, I Billig, J. P. Card, and B. J. Yates

Transneuronal tracing of neural pathways influencing both diaphragm and genioglossal muscle activity in the ferret
J Appl Physiol 95: 1453-1459, 2003. First published June 27, 2003; 10.1152/japplphysiol.00558.2003 [Abstract] [Full Text]  

Darija Bakovic, Zoran Valic, Davor Eterovic, Ivica Vukovic, Ante Obad, Ivana Marinovic-Terzic, and Zeljko Dujic

Spleen volume and blood flow response to repeated breath-hold apneas
J Appl Physiol 95: 1460-1466, 2003. First published June 20, 2003; 10.1152/japplphysiol.00221.2003 [Abstract] [Full Text]  

D Shirley, P. W. Hodges, A. E. M. Eriksson, and S. C. Gandevia

Spinal stiffness changes throughout the respiratory cycle
J Appl Physiol 95: 1467-1475, 2003; 10.1152/japplphysiol.00939.2002 [Abstract] [Full Text]  

J. L. Darques, D Bendahan, M Roussel, B Giannesini, F Tagliarini, Y Le Fur, P. J. Cozzone, and Y Jammes

Combined in situ analysis of metabolic and myoelectrical changes associated with electrically induced fatigue
J Appl Physiol 95: 1476-1484, 2003. First published June 20, 2003; 10.1152/japplphysiol.00230.2003 [Abstract] [Full Text]  

Minoru Shinohara, Yasuhide Yoshitake, Motoki Kouzaki, Hideoki Fukuoka, and Tetsuo Fukunaga

Strength training counteracts motor performance losses during bed rest
J Appl Physiol 95: 1485-1492, 2003. First published June 27, 2003; 10.1152/japplphysiol.01173.2002 [Abstract] [Full Text]  

Joseph C. Daley, III, Mazhar H. Khan, Cynthia S. Hogeman, and Lawrence I. Sinoway

Autonomic and vascular responses to reduced limb perfusion
J Appl Physiol 95: 1493-1498, 2003. First published June 27, 2003; 10.1152/japplphysiol.00344.2002 [Abstract] [Full Text]  

Michelle McGuire, Yi Zhang, David P. White, and Liming Ling

Chronic intermittent hypoxia enhances ventilatory long-term facilitation in awake rats
J Appl Physiol 95: 1499-1508, 2003. First published June 20, 2003; 10.1152/japplphysiol.00044.2003 [Abstract] [Full Text]  

Lee A. Danielson and Kirk P. Conrad

Time course and dose response of relaxin-mediated renal vasodilation, hyperfiltration, and changes in plasma osmolality in conscious rats
J Appl Physiol 95: 1509-1514, 2003. First published June 20, 2003; 10.1152/japplphysiol.00545.2003 [Abstract] [Full Text]  

L Rochette, S. K. Hunter, N Place, and R Lepers

Activation varies among the knee extensor muscles during a submaximal fatiguing contraction in the seated and supine postures
J Appl Physiol 95: 1515-1522, 2003; 10.1152/japplphysiol.00334.2003 [Abstract] [Full Text]  

Michael J. Christopher, Zhi-Ping Chen, Christian Rantzau, Bruce E. Kemp, and Frank P. Alford

Skeletal muscle basal AMP-activated protein kinase activity is chronically elevated in alloxan-diabetic dogs: impact of exercise
J Appl Physiol 95: 1523-1530, 2003. First published June 27, 2003; 10.1152/japplphysiol.00199.2003 [Abstract] [Full Text]  

Fabrice Favret, Kyle K. Henderson, Jean-Paul Richalet, and Norberto C. Gonzalez

Effects of exercise training on acclimatization to hypoxia: systemic O₂ transport during maximal exercise
J Appl Physiol 95: 1531-1541, 2003. First published June 27, 2003; 10.1152/japplphysiol.01220.2001 [Abstract] [Full Text]  

Francisco García-Río, José M. Pino, Angeles Ruiz, Salvador Díaz, Concepción Prados, and José Villamor

Accuracy of noninvasive estimates of respiratory muscle effort during spontaneous breathing in restrictive diseases
J Appl Physiol 95: 1542-1549, 2003. First published June 13, 2003; 10.1152/japplphysiol.01010.2002 [Abstract] [Full Text]  

R. W. Bavis, E. B. Olson, Jr., E. H. Vidruk, G. E. Bisgard, and G. S. Mitchell

Level and duration of developmental hyperoxia influence impairment of hypoxic phrenic responses in rats
J Appl Physiol 95: 1550-1559, 2003. First published June 20, 2003; 10.1152/japplphysiol.01043.2002 [Abstract] [Full Text]  

Kristina Kairaitis, Radha Parikh, Rosie Stavrinou, Sarah Garlick, Jason P. Kirkness, John R. Wheatley, and Terence C. Amis

Upper airway extraluminal tissue pressure fluctuations during breathing in rabbits
J Appl Physiol 95: 1560-1566, 2003. First published June 27, 2003; 10.1152/japplphysiol.00432.2003 [Abstract] [Full Text]  

Fumio Yamazaki and Kunshige Hamasaki

Heat acclimation increases skin vasodilation and sweating but not cardiac baroreflex responses in heat-stressed humans
J Appl Physiol 95: 1567-1574, 2003. First published June 6, 2003; 10.1152/japplphysiol.00063.2003 [Abstract] [Full Text]  

Ken-ichi Iwasaki, Rong Zhang, Julie H. Zuckerman, and Benjamin D. Levine

Dose-response relationship of the cardiovascular adaptation to endurance training in healthy adults: how much training for what benefit?
J Appl Physiol 95: 1575-1583, 2003. First published June 27, 2003; 10.1152/japplphysiol.00482.2003 [Abstract] [Full Text]  

Angel A. Zaninovich, Inés Rebagliati, Marcela Raíces, Conrado Ricci, and Karl Hagmüller

Mitochondrial respiration in muscle and liver from cold-acclimated hypothyroid rats
J Appl Physiol 95: 1584-1590, 2003. First published June 27, 2003; 10.1152/japplphysiol.00363.2003 [Abstract] [Full Text]  

C. Harrington, T. Kirjavainen, A. Teng, and C. E. Sullivan

nCPAP improves abnormal autonomic function in at-risk-for-SIDS infants with OSA
J Appl Physiol 95: 1591-1597, 2003. First published May 2, 2003; 10.1152/japplphysiol.00354.2002 [Abstract] [Full Text]  

C. M. B. Edwards, P. P. Corkery, and A. V. Edwards

Submandibular responses to stimulation of the parasympathetic innervation in anesthetized sheep
J Appl Physiol 95: 1598-1605, 2003. First published July 11, 2003; 10.1152/japplphysiol.00991.2002 [Abstract] [Full Text]  

Michael J. McKenna, Steve F. Fraser, Jia L. Li, Xiao N. Wang, Michael F. Carey, Eleonora A. Side, Judith Morton, Gregory I. Snell, Keld Kjeldsen, and Trevor J. Williams

Impaired muscle Ca²⁺ and K⁺ regulation contribute to poor exercise performance post-lung transplantation
J Appl Physiol 95: 1606-1616, 2003. First published June 13, 2003; 10.1152/japplphysiol.01175.2002 [Abstract] [Full Text]  

Kurt W. Haubold, David L. Allen, Yassemi Capetanaki, and Leslie A. Leinwand

Loss of desmin leads to impaired voluntary wheel running and treadmill exercise performance
J Appl Physiol 95: 1617-1622, 2003. First published July 3, 2003; 10.1152/japplphysiol.00408.2003 [Abstract] [Full Text]  

Masako Endo, Shinko Tauchi, Naoyuki Hayashi, Shunsaku Koga, Harry B. Rossiter, and Yoshiyuki Fukuba

Facial cooling-induced bradycardia does not slow pulmonary V^.O₂ kinetics at the onset of high-intensity exercise
J Appl Physiol 95: 1623-1631, 2003. First published July 3, 2003; 10.1152/japplphysiol.00415.2003 [Abstract] [Full Text]  

François Billaut, Magali Giacomoni, and Guy Falgairette

Maximal intermittent cycling exercise: effects of recovery duration and gender
J Appl Physiol 95: 1632-1637, 2003. First published June 6, 2003; 10.1152/japplphysiol.00983.2002 [Abstract] [Full Text]  

J. David Symons, Yoko Hayashi, and Jodi L. Ensunsa

Improved coronary vascular function evoked by high-intensity treadmill training is maintained in arteries exposed to ischemia and reperfusion
J Appl Physiol 95: 1638-1647, 2003. First published June 20, 2003; 10.1152/japplphysiol.01168.2002 [Abstract] [Full Text]  

M. A. E. Oskouei, B. C. F. van Mazijk, M. H. C. Schuiling, and W Herzog

Variability in the interpolated twitch torque for maximal and submaximal voluntary contractions
J Appl Physiol 95: 1648-1655, 2003. First published May 30, 2003; 10.1152/japplphysiol.01189.2002 [Abstract] [Full Text]  

C. A. Rivera, M. H. Tcharmtchi, L. Mendoza, and C. W. Smith

Endotoxemia and hepatic injury in a rodent model of hindlimb unloading
J Appl Physiol 95: 1656-1663, 2003. First published June 6, 2003; 10.1152/japplphysiol.00302.2003 [Abstract] [Full Text]  

Martin Flück, Magali Kitzmann, Christoph Däpp, Matthias Chiquet, Frank W. Booth, and Anne Fernandez

Transient induction of cyclin A in loaded chicken skeletal muscle
J Appl Physiol 95: 1664-1671, 2003. First published June 20, 2003; 10.1152/japplphysiol.00276.2003 [Abstract] [Full Text]  

Ritu Chatrath, Karen L. Ronningen, Peter LaBreche, Sandra R. Severson, Muthuvel Jayachandran, Margarita P. Bracamonte, and Virginia M. Miller

Effect of puberty on coronary arteries from female pigs
J Appl Physiol 95: 1672-1680, 2003. First published June 6, 2003; 10.1152/japplphysiol.00099.2003 [Abstract] [Full Text]  

Clarke G. Tankersley, Jessica A. Shank, Susan E. Flanders, Shawn E. Soutiere, Richard Rabold, Wayne Mitzner, and Elizabeth M. Wagner

Changes in lung permeability and lung mechanics accompany homeostatic instability in senescent mice
J Appl Physiol 95: 1681-1687, 2003. First published June 6, 2003; 10.1152/japplphysiol.00190.2003 [Abstract] [Full Text]  

INNOVATIVE METHODOLOGY

Heiner Post, Jan Kajstura, Biao Lei, William C. Sessa, Barry Byrne, Piero Anversa, Thomas H. Hintze, and Fabio A. Recchia

Adeno-associated virus mediated gene delivery into coronary microvessels of chronically instrumented dogs
J Appl Physiol 95: 1688-1694, 2003. First published July 3, 2003; 10.1152/japplphysiol.00896.2002 [Abstract] [Full Text]  

Zoltán Hantos, Rachel A. Collins, Debra J. Turner, Tibor Z. Jánosi, and Peter D. Sly

Tracking of airway and tissue mechanics during TLC maneuvers in mice
J Appl Physiol 95: 1695-1705, 2003. First published May 30, 2003; 10.1152/japplphysiol.00104.2003 [Abstract] [Full Text]  

HIGHLIGHTED TOPICS

Brian T. Weinert and Poala S. Timiras

Invited Review: Theories of aging
J Appl Physiol 95: 1706-1716, 2003; 10.1152/japplphysiol.00288.2003 [Abstract] [Full Text]  

Timothy J. Doherty

Invited Review: Aging and sarcopenia
J Appl Physiol 95: 1717-1727, 2003; 10.1152/japplphysiol.00347.2003 [Abstract] [Full Text]  

Margaret-Mary G. Wilson and John E. Morley

Invited Review: Aging and energy balance
J Appl Physiol 95: 1728-1736, 2003; 10.1152/japplphysiol.00313.2003 [Abstract] [Full Text]  

Gary C. Sieck

Commentary on Selected Contributions
J Appl Physiol 95: 1737-1738, 2003; 10.1152/japplphysiol.00806.2003 [Full Text]  

Jeremy M. LaMothe, Russell T. Hepple, and Ronald F. Zernicke

Selected Contribution: Bone adaptation with aging and long-term caloric restriction in Fischer 344 x Brown-Norway F1-hybrid rats
J Appl Physiol 95: 1739-1745, 2003. First published June 13, 2003; 10.1152/japplphysiol.00079.2003 [Abstract] [Full Text]  

Greg G. Geary and John N. Buchholz

Selected Contribution: Effects of aging on cerebrovascular tone and [Ca²⁺]_i
J Appl Physiol 95: 1746-1754, 2003. First published June 20, 2003; 10.1152/japplphysiol.00275.2003 [Abstract] [Full Text]  

C. Di Giulio, M. Cacchio, G. Bianchi, C. Rapino, and C. Di Ilio

Selected Contribution: Carotid body as a model for aging studies: is there a link between oxygen and aging?
J Appl Physiol 95: 1755-1758, 2003. First published July 18, 2003; 10.1152/japplphysiol.00406.2003 [Abstract] [Full Text]  

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