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Table of Contents: April 2005; 98 (4) [Index by Author] [Editorial Board] [Cover]
EDITORIAL
INVITED REVIEW
TRANSLATIONAL PHYSIOLOGY
ARTICLES
INNOVATIVE METHODOLOGY
HIGHLIGHTED TOPICS
LETTERS TO THE EDITOR
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EDITORIAL

Gary C. Sieck
Biomechanics and Mechanotransduction in Cells and Tissues
J Appl Physiol 98: 1153-1153, 2005; doi:10.1152/japplphysiol.00057.2005 [Full Text] [PDF]  


INVITED REVIEW

Anne Marie W. Petersen and Bente Klarlund Pedersen
The anti-inflammatory effect of exercise
J Appl Physiol 98: 1154-1162, 2005; doi:10.1152/japplphysiol.00164.2004 [Abstract] [Full Text] [PDF]  


TRANSLATIONAL PHYSIOLOGY

Geoffrey A. Head, Christopher M. Reid, and Elena V. Lukoshkova
Nonsymmetrical double logistic analysis of ambulatory blood pressure recordings
J Appl Physiol 98: 1511-1518, 2005. First published November 5, 2004; doi:10.1152/japplphysiol.00647.2004 [Abstract] [Full Text] [PDF]  

David S. Ditor, Mark V. Kamath, Maureen J. MacDonald, Joanne Bugaresti, Neil McCartney, and Audrey L. Hicks
Effects of body weight-supported treadmill training on heart rate variability and blood pressure variability in individuals with spinal cord injury
J Appl Physiol 98: 1519-1525, 2005. First published November 24, 2004; doi:10.1152/japplphysiol.01004.2004 [Abstract] [Full Text] [PDF]  

Michael Fayon, Eric Dumas De La Roque, Patrick Berger, Hugues Begueret, Olga Ousova, Mathieu Molimard, and Roger Marthan
Increased relaxation of immature airways to {beta}2-adrenoceptor agonists is related to attenuated expression of postjunctional smooth muscle muscarinic M2 receptors
J Appl Physiol 98: 1526-1533, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.00948.2004 [Abstract] [Full Text] [PDF]  

Adrian S. Fairey, Kerry S. Courneya, Catherine J. Field, Gordon J. Bell, Lee W. Jones, and John R. Mackey
Randomized controlled trial of exercise and blood immune function in postmenopausal breast cancer survivors
J Appl Physiol 98: 1534-1540, 2005; doi:10.1152/japplphysiol.00566.2004 [Abstract] [Full Text] [PDF]  


ARTICLES

Guy A. MacGowan, Jennifer Rager, Sanjeev G. Shroff, and Michael A. Mathier
In vivo {alpha}-adrenergic responses and troponin I phosphorylation: anesthesia interactions
J Appl Physiol 98: 1163-1170, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.00959.2004 [Abstract] [Full Text] [PDF]  

Akram Khan, Mansour Qurashi, Kim Kwiatkowski, Don Cates, and Henrique Rigatto
Measurement of the CO2 apneic threshold in newborn infants: possible relevance for periodic breathing and apnea
J Appl Physiol 98: 1171-1176, 2005; doi:10.1152/japplphysiol.00574.2003 [Abstract] [Full Text] [PDF]  

Paul C. Johnson, Kim Vandegriff, Amy G. Tsai, and Marcos Intaglietta
Effect of acute hypoxia on microcirculatory and tissue oxygen levels in rat cremaster muscle
J Appl Physiol 98: 1177-1184, 2005; doi:10.1152/japplphysiol.00591.2004 [Abstract] [Full Text] [PDF]  

Julia M. Giger, Fadia Haddad, Anqi X. Qin, Ming Zeng, and Kenneth M. Baldwin
Effect of unloading on type I myosin heavy chain gene regulation in rat soleus muscle
J Appl Physiol 98: 1185-1194, 2005. First published December 10, 2004; doi:10.1152/japplphysiol.01099.2004 [Abstract] [Full Text] [PDF]  

Michelle McGuire and Liming Ling
Ventilatory long-term facilitation is greater in 1- vs. 2-mo-old awake rats
J Appl Physiol 98: 1195-1201, 2005. First published December 10, 2004; doi:10.1152/japplphysiol.00996.2004 [Abstract] [Full Text] [PDF]  

R. Grant Highstead, Kevin D. Tipton, Daniel L. Creson, Robert R. Wolfe, and Arny A. Ferrando
Incidence of associated events during the performance of invasive procedures in healthy human volunteers
J Appl Physiol 98: 1202-1206, 2005. First published November 24, 2004; doi:10.1152/japplphysiol.01076.2004 [Abstract] [Full Text] [PDF]  

Thad E. Wilson, Jian Cui, and Craig G. Crandall
Mean body temperature does not modulate eccrine sweat rate during upright tilt
J Appl Physiol 98: 1207-1212, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.00648.2004 [Abstract] [Full Text] [PDF]  

Joseph F. Signorile, Michelle P. Carmel, Shenghan Lai, and Bernard A. Roos
Early plateaus of power and torque gains during high- and low-speed resistance training of older women
J Appl Physiol 98: 1213-1220, 2005; doi:10.1152/japplphysiol.00742.2004 [Abstract] [Full Text] [PDF]  

D. S. Rubink and W. W. Winder
Effect of phosphorylation by AMP-activated protein kinase on palmitoyl-CoA inhibition of skeletal muscle acetyl-CoA carboxylase
J Appl Physiol 98: 1221-1227, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.00621.2004 [Abstract] [Full Text] [PDF]  

Bert O. Eijnde, Wim Derave, Jørgen F. P. Wojtaszewski, Erik A. Richter, and Peter Hespel
AMP kinase expression and activity in human skeletal muscle: effects of immobilization, retraining, and creatine supplementation
J Appl Physiol 98: 1228-1233, 2005. First published October 29, 2004; doi:10.1152/japplphysiol.00665.2004 [Abstract] [Full Text] [PDF]  

M. R. Hodges, C. Opansky, B. Qian, S. Davis, J. M. Bonis, K. Krause, L. G. Pan, and H. V. Forster
Carotid body denervation alters ventilatory responses to ibotenic acid injections or focal acidosis in the medullary raphe
J Appl Physiol 98: 1234-1242, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.01011.2004 [Abstract] [Full Text] [PDF]  

Stéphane Baudry, Malgorzata Klass, and Jacques Duchateau
Postactivation potentiation influences differently the nonlinear summation of contractions in young and elderly adults
J Appl Physiol 98: 1243-1250, 2005. First published November 19, 2004; doi:10.1152/japplphysiol.00735.2004 [Abstract] [Full Text] [PDF]  

William G. Schrage, Niki M. Dietz, John H. Eisenach, and Michael J. Joyner
Agonist-dependent variablity of contributions of nitric oxide and prostaglandins in human skeletal muscle
J Appl Physiol 98: 1251-1257, 2005. First published November 24, 2004; doi:10.1152/japplphysiol.00966.2004 [Abstract] [Full Text] [PDF]  

Veronique L. Billat, Etienne Mouisel, Natacha Roblot, and Judith Melki
Inter- and intrastrain variation in mouse critical running speed
J Appl Physiol 98: 1258-1263, 2005. First published November 12, 2004; doi:10.1152/japplphysiol.00991.2004 [Abstract] [Full Text] [PDF]  

Sawako Yoshikawa, Takashige Miyahara, Susan D. Reynolds, Barry R. Stripp, Mircea Anghelescu, Fabien G. Eyal, and James C. Parker
Clara cell secretory protein and phospholipase A2 activity modulate acute ventilator-induced lung injury in mice
J Appl Physiol 98: 1264-1271, 2005. First published December 17, 2004; doi:10.1152/japplphysiol.01150.2004 [Abstract] [Full Text] [PDF]  

Umit K. Senturk, Ozlem Yalcin, Filiz Gunduz, Oktay Kuru, Herbert J. Meiselman, and Oguz K. Baskurt
Effect of antioxidant vitamin treatment on the time course of hematological and hemorheological alterations after an exhausting exercise episode in human subjects
J Appl Physiol 98: 1272-1279, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.00875.2004 [Abstract] [Full Text] [PDF]  

Philip A. Ades, Patrick D. Savage, Martin Brochu, Marc D. Tischler, N. Melinda Lee, and Eric T. Poehlman
Resistance training increases total daily energy expenditure in disabled older women with coronary heart disease
J Appl Physiol 98: 1280-1285, 2005; doi:10.1152/japplphysiol.00360.2004 [Abstract] [Full Text] [PDF]  

Natasha R. Saunders, Kyra E. Pyke, and Michael E. Tschakovsky
Dynamic response characteristics of local muscle blood flow regulatory mechanisms in human forearm exercise
J Appl Physiol 98: 1286-1296, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.01118.2004 [Abstract] [Full Text] [PDF]  

Tadafumi Adachi, Dean M. Robinson, Gareth B. Miles, and Gregory D. Funk
Noradrenergic modulation of XII motoneuron inspiratory activity does not involve {alpha}2-receptor inhibition of the Ih current or presynaptic glutamate release
J Appl Physiol 98: 1297-1308, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.00977.2004 [Abstract] [Full Text] [PDF]  

O. Ertracht, R. Arieli, Y. Arieli, R. Ron, Z. Erlichman, and Y. Adir
Optimal oxygen pressure and time for reduced bubble formation in theN2-saturated decompressed prawn
J Appl Physiol 98: 1309-1313, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.01051.2004 [Abstract] [Full Text] [PDF]  

Keith C. DeRuisseau, Andreas N. Kavazis, Melissa A. Deering, Darin J. Falk, Darin Van Gammeren, Tossaporn Yimlamai, George A. Ordway, and Scott K. Powers
Mechanical ventilation induces alterations of the ubiquitin-proteasome pathway in the diaphragm
J Appl Physiol 98: 1314-1321, 2005. First published November 19, 2004; doi:10.1152/japplphysiol.00993.2004 [Abstract] [Full Text] [PDF]  

Mirela B. Dias, Maria C. Almeida, Evelin C. Carnio, and Luiz G. S. Branco
Role of nitric oxide in tolerance to lipopolysaccharide in mice
J Appl Physiol 98: 1322-1327, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.01243.2004 [Abstract] [Full Text] [PDF]  

Willy Hwang, Neil G. Kelly, and Aladin M. Boriek
Passive mechanics of muscle tendinous junction of canine diaphragm
J Appl Physiol 98: 1328-1333, 2005; doi:10.1152/japplphysiol.00816.2004 [Abstract] [Full Text] [PDF]  

Catherine O'Brien
Reproducibility of the cold-induced vasodilation response in the human finger
J Appl Physiol 98: 1334-1340, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.00859.2004 [Abstract] [Full Text] [PDF]  

Linda M. Szymanski, Craig M. Kessler, and Bo Fernhall
Relationship of physical fitness, hormone replacement therapy, and hemostatic risk factors in postmenopausal women
J Appl Physiol 98: 1341-1348, 2005. First published December 10, 2004; doi:10.1152/japplphysiol.00622.2004 [Abstract] [Full Text] [PDF]  

Denise M. O'Driscoll, Konstantinos Kostikas, Anita K. Simonds, and Mary J. Morrell
Occlusion of the upper airway does not augment the cardiovascular response to arousal from sleep in humans
J Appl Physiol 98: 1349-1355, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.00706.2004 [Abstract] [Full Text] [PDF]  

Chi-Ming Hai and Hak Rim Kim
An expanded latch-bridge model of protein kinase C-mediated smooth muscle contraction
J Appl Physiol 98: 1356-1365, 2005. First published November 19, 2004; doi:10.1152/japplphysiol.00834.2004 [Abstract] [Full Text] [PDF]  

Nis Hjortskov, Jørgen Skotte, Christian Hye-Knudsen, and Nils Fallentin
Sympathetic outflow enhances the stretch reflex response in the relaxed soleus muscle in humans
J Appl Physiol 98: 1366-1370, 2005. First published November 12, 2004; doi:10.1152/japplphysiol.00955.2004 [Abstract] [Full Text] [PDF]  

Brendon J. Gurd, Barry W. Scheuermann, Donald H. Paterson, and John M. Kowalchuk
Prior heavy-intensity exercise speeds V·O2 kinetics during moderate-intensity exercise in young adults
J Appl Physiol 98: 1371-1378, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.01028.2004 [Abstract] [Full Text] [PDF]  

Jatin G. Burniston, Lip-Bun Tan, and David F. Goldspink
{beta}2-Adrenergic receptor stimulation in vivo induces apoptosis in the rat heart and soleus muscle
J Appl Physiol 98: 1379-1386, 2005. First published December 10, 2004; doi:10.1152/japplphysiol.00642.2004 [Abstract] [Full Text] [PDF]  

John K. Young, Mingfei Wu, Kebreten F. Manaye, Prabha Kc, Joanne S. Allard, Serdia O. Mack, and Musa A. Haxhiu
Orexin stimulates breathing via medullary and spinal pathways
J Appl Physiol 98: 1387-1395, 2005. First published November 19, 2004; doi:10.1152/japplphysiol.00914.2004 [Abstract] [Full Text] [PDF]  

Eric J. Stevenson, Alan Koncarevic, Paul G. Giresi, Robert W. Jackman, and Susan C. Kandarian
Transcriptional profile of a myotube starvation model of atrophy
J Appl Physiol 98: 1396-1406, 2005. First published December 17, 2004; doi:10.1152/japplphysiol.01055.2004 [Abstract] [Full Text] [PDF]  

Hidemi Fujino, Hisaharu Kohzuki, Isao Takeda, Takahiko Kiyooka, Takehiro Miyasaka, Satoshi Mohri, Juichiro Shimizu, and Fumihiko Kajiya
Regression of capillary network in atrophied soleus muscle induced by hindlimb unweighting
J Appl Physiol 98: 1407-1413, 2005. First published December 10, 2004; doi:10.1152/japplphysiol.00961.2004 [Abstract] [Full Text] [PDF] [Supplement Data]  

Antonino Coppola, Ludovico Coppola, Liliana dalla Mora, Francesco M. Limongelli, Antonio Grassia, Luigia Mastrolorenzo, Giorgio Gombos, and Giacomo Lucivero
Vigorous exercise acutely changes platelet and B-lymphocyte CD39 expression
J Appl Physiol 98: 1414-1419, 2005; doi:10.1152/japplphysiol.00315.2004 [Abstract] [Full Text] [PDF]  

Michael C. Hogan, Creed M. Stary, Robert S. Balaban, and Christian A. Combs
NAD(P)H fluorescence imaging of mitochondrial metabolism in contracting Xenopus skeletal muscle fibers: effect of oxygen availability
J Appl Physiol 98: 1420-1426, 2005. First published December 10, 2004; doi:10.1152/japplphysiol.00849.2004 [Abstract] [Full Text] [PDF]  

Junichi Ushiyama, Kei Masani, Motoki Kouzaki, Hiroaki Kanehisa, and Tetsuo Fukunaga
Difference in aftereffects following prolonged Achilles tendon vibration on muscle activity during maximal voluntary contraction among plantar flexor synergists
J Appl Physiol 98: 1427-1433, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.00613.2004 [Abstract] [Full Text] [PDF]  

Lauren D. Black, Kelly K. Brewer, Shirley M. Morris, Barbara M. Schreiber, Paul Toselli, Matthew A. Nugent, Bela Suki, and Phillip J. Stone
Effects of elastase on the mechanical and failure properties of engineered elastin-rich matrices
J Appl Physiol 98: 1434-1441, 2005. First published January 7, 2005; doi:10.1152/japplphysiol.00921.2004 [Abstract] [Full Text] [PDF]  

Qiuli Liu and Margaret T. T. Wong-Riley
Postnatal developmental expressions of neurotransmitters and receptors in various brain stem nuclei of rats
J Appl Physiol 98: 1442-1457, 2005. First published December 23, 2004; doi:10.1152/japplphysiol.01301.2004 [Abstract] [Full Text] [PDF]  

Hiroshi Hasegawa, Takayuki Ishiwata, Takehito Saito, Toru Yazawa, Yasutsugu Aihara, and Romain Meeusen
Inhibition of the preoptic area and anterior hypothalamus by tetrodotoxin alters thermoregulatory functions in exercising rats
J Appl Physiol 98: 1458-1462, 2005. First published December 23, 2004; doi:10.1152/japplphysiol.00916.2004 [Abstract] [Full Text] [PDF]  

Jay T. Williams, Mollie P. Pricher, and John R. Halliwill
Is postexercise hypotension related to excess postexercise oxygen consumption through changes in leg blood flow?
J Appl Physiol 98: 1463-1468, 2005. First published December 17, 2004; doi:10.1152/japplphysiol.01211.2004 [Abstract] [Full Text] [PDF]  

Insook Kim, Kathleen M. Boyle, and John L. Carroll
Postnatal development of E-4031-sensitive potassium current in rat carotid chemoreceptor cells
J Appl Physiol 98: 1469-1477, 2005. First published December 10, 2004; doi:10.1152/japplphysiol.01254.2003 [Abstract] [Full Text] [PDF]  

Natalia Skorohod and Donovan B. Yeates
Superoxide dismutase failed to attenuate allergen-induced nasal congestion in ragweed-sensitized dogs
J Appl Physiol 98: 1478-1486, 2005. First published December 17, 2004; doi:10.1152/japplphysiol.00910.2004 [Abstract] [Full Text] [PDF]  

Dario Farina, Marco Gazzoni, and Federico Camelia
Conduction velocity of low-threshold motor units during ischemic contractions performed with surface EMG feedback
J Appl Physiol 98: 1487-1494, 2005. First published November 12, 2004; doi:10.1152/japplphysiol.01032.2004 [Abstract] [Full Text] [PDF]  

Dario Farina, Lars Arendt-Nielsen, and Thomas Graven-Nielsen
Spike-triggered average torque and muscle fiber conduction velocity of low-threshold motor units following submaximal endurance contractions
J Appl Physiol 98: 1495-1502, 2005. First published November 12, 2004; doi:10.1152/japplphysiol.01127.2004 [Abstract] [Full Text] [PDF]  


INNOVATIVE METHODOLOGY

Lisa S. Ziemer, William M. F. Lee, Sergei A. Vinogradov, Chandra Sehgal, and David F. Wilson
Oxygen distribution in murine tumors: characterization using oxygen-dependent quenching of phosphorescence
J Appl Physiol 98: 1503-1510, 2005. First published December 3, 2004; doi:10.1152/japplphysiol.01140.2004 [Abstract] [Full Text] [PDF]  


HIGHLIGHTED TOPICS

Gary C. Sieck
Commentary 
J Appl Physiol 98: 1541-1541, 2005; doi:10.1152/japplphysiol.00058.2005 [Full Text] [PDF]  

Hans-Günther Döbereiner, Benjamin J. Dubin-Thaler, Gregory Giannone, and Michael P. Sheetz
Invited Review  Force sensing and generation in cell phases: analyses of complex functions
J Appl Physiol 98: 1542-1546, 2005; doi:10.1152/japplphysiol.01181.2004 [Abstract] [Full Text] [PDF]  

Penelope C. Georges and Paul A. Janmey
Invited Review  Cell type-specific response to growth on soft materials
J Appl Physiol 98: 1547-1553, 2005; doi:10.1152/japplphysiol.01121.2004 [Abstract] [Full Text] [PDF]  

Anne Claire Bellott, Kalpit C. Patel, and Thomas J. Burkholder
Reduction of caveolin-3 expression does not inhibit stretch-induced phosphorylation of ERK2 in skeletal muscle myotubes
J Appl Physiol 98: 1554-1561, 2005. First published October 29, 2004; doi:10.1152/japplphysiol.01070.2004 [Abstract] [Full Text] [PDF]  

Troy A. Hornberger, R. D. Mateja, E. R. Chin, J. L. Andrews, and K. A. Esser
Aging does not alter the mechanosensitivity of the p38, p70S6k, and JNK2 signaling pathways in skeletal muscle
J Appl Physiol 98: 1562-1566, 2005. First published September 10, 2004; doi:10.1152/japplphysiol.00870.2004 [Abstract] [Full Text] [PDF]  

Xavier Trepat, Mireia Grabulosa, Lara Buscemi, Fèlix Rico, Ramon Farré, and Daniel Navajas
Thrombin and histamine induce stiffening of alveolar epithelial cells
J Appl Physiol 98: 1567-1574, 2005. First published November 19, 2004; doi:10.1152/japplphysiol.00925.2004 [Abstract] [Full Text] [PDF]  

Barbara J. Lutjemeier, Akira Miura, Barry W. Scheuermann, Shunsaku Koga, Dana K. Townsend, and Thomas J. Barstow
Muscle contraction-blood flow interactions during upright knee extension exercise in humans
J Appl Physiol 98: 1575-1583, 2005. First published November 19, 2004; doi:10.1152/japplphysiol.00219.2004 [Abstract] [Full Text] [PDF]  


LETTERS TO THE EDITOR

Adriaan M. Kamper, Anton J. M. de Craen, John B. Buckwalter, Jessica C. Taylor, Jason J. Hamann, and Philip S. Clifford
Role of Nitric Oxide and {alpha}-Adrenergic Receptor Responsiveness in Exercising Skeletal Muscle
J Appl Physiol 98: 1584-1585, 2005; doi:10.1152/japplphysiol.00947.2004 [Abstract] [Full Text] [PDF]  


To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstracts' button. To see one abstract at a time, click its [Abstract] link.


Cover

Cover Image Cover:

The April through June 2005 Highlighted Topics series examines the effects of mechanical force on cells and tissues and the mechanisms by which cells sense mechanical signals and transduce them into downstream pathways that regulate growth, adaptation, and physiological properties. Articles will focus on the mechanisms by which cells sense and respond to matrix rigidity, transduction processes involved in regulating cell growth and phenotype, and biomechanical properties of connective tissues and the role of these properties in the etiology of diseases such as emphysema. We acknowledge Steve Graepel, illustrator of the cover design. This illustration is copyrighted by Steve Graepel and reproduced with permission.



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